GET-Evidence

 = Genotype + Environment = Trait (GET) Evidence Database = 

The '''GET Evidence''' project was started by Abraham Rosenbaum, Joe Thakuria, Xiaodi Wu and Alexander Wait Zaranek to help the [http://personalgenomes.org Personal Genome Project], the clinical genetics community, and, the general public interpret individual genomes.  The database is closely integrated with [wiki:Trait-o-matic].

You can find the PGP production server at:

 * http://evidence.personalgenomes.org

A development sandbox can be found at: 

 * http://evidence-dev.personalgenomes.org

Many contributors helped make '''GET Evidence''' possible. You can find specific contributions at: 

 * http://evidence.personalgenomes.org/editors

Please help the project by editing the database or making suggestions on the wiki!  

 == To Do ==

[wiki:GET-Evidence/23andWe]

 == Field Descriptions and Definitions ==

 * Short Summary: Each of these fields is a sliding scale of 0-5 where 0 represents no evidence and 5 strong evidence that the Impact is correct.

   a. Computational: Average of predictions generated by SIFT, !PolyPhen and NBLOSUM.

   a. Molecular and Cellular: Results of enzyme extracts, cell lines and animal models.

   a. Clinical

      i. Population: Odds Ratio

      i. Family: LOD score.

      i. Outcomes: The ability to act on this mutation.

 * Impact

   a. Pathogenic

   a. Putative Pathogenic

   a. Putative Benign

   a. Benign

   a. Putative Protective

   a. Protective

   a. Unknown

 * Inheritance Pattern

   a. Dominant

   a. Recessive

   a. Other

   a. Unknown

 * Summary of published research, and additional commentary

 * Allele Frequency

 * Publications

 * Genomes

 * Other External References

   a. dbSNP

   a. Genetests

   a. Web Search Results

 * Edit History

 == Suggestions == 

 * your suggestion here.