Wiki » History » Version 9
Jason Bobe, 02/01/2010 02:30 PM
1 | 1 | Jason Bobe | = Genotype + Environment = Trait (GET) Evidence Database = |
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3 | The '''GET Evidence''' project was started by Abraham Rosenbaum, Joe Thakuria, Xiaodi Wu and Alexander Wait Zaranek to help the [http://personalgenomes.org Personal Genome Project], the clinical genetics community, and, the general public interpret individual genomes. The database is closely integrated with [wiki:Trait-o-matic]. |
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5 | You can find the PGP production server at: |
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6 | * http://evidence.personalgenomes.org |
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8 | A development sandbox can be found at: |
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9 | * http://evidence-dev.personalgenomes.org |
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11 | Many contributors helped make '''GET Evidence''' possible. You can find specific contributions at: |
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12 | * http://evidence.personalgenomes.org/editors |
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14 | Please help the project by editing the database or making suggestions on the wiki! |
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16 | 2 | Jason Bobe | == To Do == |
17 | [wiki:GET-Evidence/23andWe] |
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18 | 1 | Jason Bobe | |
19 | 4 | Jason Bobe | == Field Descriptions and Definitions == |
20 | 6 | Jason Bobe | * Short Summary: Each of these fields is a sliding scale of 0-5 where 0 represents no evidence and 5 strong evidence that the Impact is correct. |
21 | 8 | Tom Clegg | a. Computational: Average of predictions generated by SIFT, !PolyPhen and NBLOSUM. |
22 | 7 | Jason Bobe | a. Molecular and Cellular: Results of enzyme extracts, cell lines and animal models. |
23 | 5 | Jason Bobe | a. Clinical |
24 | 7 | Jason Bobe | i. Population: Odds Ratio |
25 | i. Family: LOD score. |
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26 | i. Outcomes: The ability to act on this mutation. |
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27 | 4 | Jason Bobe | * Impact |
28 | 5 | Jason Bobe | a. Pathogenic |
29 | a. Putative Pathogenic |
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30 | a. Putative Benign |
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31 | a. Benign |
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32 | a. Putative Protective |
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33 | a. Protective |
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34 | 9 | Jason Bobe | a. Other |
35 | 5 | Jason Bobe | a. Unknown |
36 | 4 | Jason Bobe | * Inheritance Pattern |
37 | 5 | Jason Bobe | a. Dominant |
38 | a. Recessive |
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39 | a. Other |
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40 | a. Unknown |
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41 | 4 | Jason Bobe | * Summary of published research, and additional commentary |
42 | * Allele Frequency |
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43 | * Publications |
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44 | * Genomes |
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45 | * Other External References |
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46 | 5 | Jason Bobe | a. dbSNP |
47 | a. Genetests |
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48 | a. Web Search Results |
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49 | 4 | Jason Bobe | * Edit History |
50 | 3 | Jason Bobe | |
51 | 1 | Jason Bobe | == Suggestions == |
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53 | * your suggestion here. |